Journal of Transcatheter Interventions

ABSTRACT Background Left-to-right shunting via the foramen ovale is a potential cause of paradoxical embolism. The presence of patent foramen ovale in more than 40% of patients with idiopathic ischemic stroke has led to deeper investigation of the impact of its closure on decreasing stroke recurrence rates. This study describes 20 years of experience with percutaneous patent foramen ovale occlusion performed by a single operator. Methods This sample comprised 527 patients with ischemic stroke submitted to percutaneous occlusion of patent […]

ABSTRACT The ideal antithrombotic management in patients with atrial fibrillation undergoing elective percutaneous coronary intervention or in acute coronary syndrome has not been definitively established yet. Dual antiplatelet therapy (aspirin and P2Y12 receptor inhibitors) reduces stent thrombosis and subsequent ischemic events. In turn, the presence of atrial fibrillation requires oral anticoagulation to prevent stroke and other thromboembolic complications. However, the combination of these two treatments, known as triple therapy, increases the risk of severe bleeding, with a negative prognostic impact. […]

ABSTRACT Stroke is the complication of atrial fibrillation with the greatest social and economic impact. The prevalence of this arrhythmia is epidemically growing. Although oral anticoagulants are highly effective, their contraindications, hemorrhagic complications and non-compliance of patients result in underutilization of this therapy. This review addresses aspects related to endocardial occlusion of the left atrial appendage as an alternative strategy to antithrombotic therapy, ranging from the introduction of the technique in clinical practice, the new devices being developed, technical peculiarities, […]

ABSTRACT Percutaneous left atrial appendage closure is an invasive option for cardioembolic event prevention and it is indicated for patients presenting non-valvular atrial fibrillation and oral anticoagulation therapy failure or contraindication. There is limited data addressing the technical success of percutaneous left atrial appendage closure in patients with complex anatomy and history of previous atrial septal defect repair surgery. We report a case of left atrial appendage closure performed with the LAmbre™ device (LifeTech Scientific, Shenzhen, China) in a patient […]